Jürgen Floege Selected Research

Vitamin K Deficiency

1/2022	Altered vitamin K biodistribution and metabolism in experimental and human chronic kidney disease.
1/2022	Combining phosphate binder therapy with vitamin K2 inhibits vascular calcification in an experimental animal model of kidney failure.
9/2014	Vitamin K1 to slow vascular calcification in haemodialysis patients (VitaVasK trial): a rationale and study protocol.
8/2014	Impaired vitamin K recycling in uremia is rescued by vitamin K supplementation.
2/2012	Effect of vitamin K2 supplementation on functional vitamin K deficiency in hemodialysis patients: a randomized trial.
2/2011	Circulating nonphosphorylated carboxylated matrix gla protein predicts survival in ESRD.

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.

Realize the full power of the drug-disease research graph!

Jürgen Floege Research Topics

Disease

43	Chronic Renal Insufficiency 10/2022 - 06/2009
41	IGA Glomerulonephritis (IGA Nephropathy) 01/2022 - 05/2003
34	Fibrosis (Cirrhosis) 01/2021 - 03/2005
32	Glomerulonephritis 02/2020 - 02/2000
28	Proteinuria 10/2022 - 04/2000
23	Kidney Diseases (Kidney Disease) 01/2022 - 05/2008
21	Vascular Calcification 01/2022 - 01/2002
21	Inflammation (Inflammations) 11/2020 - 08/2004
21	Secondary Hyperparathyroidism 01/2019 - 09/2007
19	Chronic Kidney Failure (Chronic Renal Failure) 11/2021 - 08/2004
17	Renal Insufficiency (Renal Failure) 05/2022 - 11/2002
17	Nephritis 04/2021 - 08/2000
12	Hyperphosphatemia 10/2022 - 01/2002
10	Cardiovascular Diseases (Cardiovascular Disease) 10/2022 - 12/2012
9	Chronic Kidney Disease-Mineral and Bone Disorder (Renal Rickets) 01/2020 - 12/2011
8	Heart Failure 10/2022 - 09/2007
8	Atrial Fibrillation 04/2022 - 11/2009
8	Albuminuria 01/2021 - 05/2002
7	Infections 01/2022 - 07/2007
7	Membranous Glomerulonephritis (Membranous Nephropathy) 10/2021 - 04/2002
6	Hemorrhage 01/2022 - 11/2002
6	Vitamin K Deficiency 01/2022 - 02/2011
6	Focal Segmental Glomerulosclerosis (Glomerulosclerosis, Focal) 10/2021 - 04/2006
6	Bone Diseases (Bone Disease) 01/2021 - 05/2008
5	Uremia 01/2022 - 05/2003
5	Lipoid Nephrosis (Glomerulonephritis, Minimal Change) 10/2021 - 05/2003
5	Ischemia 01/2020 - 10/2005
5	Hypertension (High Blood Pressure) 01/2020 - 08/2009
5	Ureteral Obstruction 01/2020 - 01/2013
5	Atherosclerosis 01/2020 - 01/2008
4	COVID-19 01/2022 - 03/2021
4	Acute Kidney Injury (Acute Renal Failure) 01/2022 - 09/2011
4	Lupus Nephritis 10/2021 - 09/2009
4	Disease Progression 01/2020 - 04/2013
4	Sclerosis 01/2020 - 04/2002
4	Neoplasms (Cancer) 01/2019 - 01/2008
4	Hyperparathyroidism 01/2018 - 04/2011
3	Type 2 Diabetes Mellitus (MODY) 01/2022 - 10/2007
3	Hypocalcemia 08/2020 - 12/2012
3	Diabetes Mellitus 08/2020 - 08/2004
3	Calciphylaxis 01/2020 - 03/2013
3	Liver Cirrhosis (Hepatic Cirrhosis) 01/2020 - 03/2012
3	Diarrhea 10/2018 - 09/2014
3	Constipation 10/2018 - 09/2014

Drug/Important Bio-Agent (IBA)

23	Proteins (Proteins, Gene)FDA Link 01/2022 - 03/2002
22	MineralsIBA 10/2022 - 01/2008
21	Phosphates (Orthophosphate)IBA 01/2022 - 01/2002
18	Cinacalcet (Sensipar)FDA Link 08/2020 - 09/2007
16	Biomarkers (Surrogate Marker)IBA 10/2022 - 07/2011
16	CalciumIBA 08/2020 - 01/2002
14	Vitamin K FDA Link 04/2022 - 04/2009
10	platelet-derived growth factor C (PDGF-C)IBA 01/2019 - 04/2002
9	Vitamin D FDA LinkGeneric 08/2020 - 06/2010
9	Sevelamer (RenaGel)FDA Link 06/2020 - 08/2004
9	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 01/2019 - 03/2002
8	CreatinineIBA 10/2022 - 03/2006
8	CollagenIBA 01/2022 - 05/2007
8	Parathyroid Hormone (Parathormone)IBA 01/2021 - 06/2010
8	sucroferric oxyhydroxideIBA 06/2020 - 06/2015
8	Platelet-Derived Growth FactorIBA 01/2018 - 03/2002
8	alpha-2-HS-GlycoproteinIBA 11/2013 - 03/2003
7	CytokinesIBA 01/2020 - 03/2005
7	Phosphorus (Red Phosphorus)IBA 10/2018 - 08/2004
7	Messenger RNA (mRNA)IBA 01/2018 - 09/2003
7	Adrenal Cortex Hormones (Corticosteroids)IBA 01/2018 - 01/2008
6	AnticoagulantsIBA 04/2022 - 03/2013
6	Matrix Gla ProteinIBA 08/2014 - 01/2002
5	GlucocorticoidsIBA 01/2022 - 12/2011
5	SodiumIBA 01/2021 - 05/2008
5	Immunoglobulin A (IgA)IBA 01/2018 - 01/2009
4	Warfarin (Coumadin)FDA LinkGeneric 04/2022 - 01/2014
4	SteroidsIBA 12/2021 - 09/2011
4	Pharmaceutical PreparationsIBA 12/2021 - 12/2012
4	Calcineurin InhibitorsIBA 01/2021 - 07/2011
4	AntibodiesIBA 01/2021 - 12/2009
4	C-Reactive ProteinIBA 01/2021 - 08/2009
4	SterolsIBA 08/2020 - 04/2011
4	MagnesiumIBA 06/2020 - 06/2015
4	Biological ProductsIBA 01/2020 - 03/2005
4	Collagen Type I (Type I Collagen)IBA 01/2020 - 05/2007
4	Adenine FDA LinkGeneric 01/2020 - 12/2013
4	LigandsIBA 01/2018 - 09/2012
4	Protein Isoforms (Isoforms)IBA 11/2014 - 01/2008
3	omega-Chloroacetophenone (Mace)IBA 10/2022 - 08/2009
3	AlbuminsIBA 10/2022 - 05/2016
3	Vitamin K 2 (Vitamin K2)IBA 01/2022 - 02/2012
3	Methylprednisolone FDA LinkGeneric 01/2022 - 01/2017
3	Antineutrophil Cytoplasmic Antibodies (ANCA)IBA 10/2021 - 09/2009
3	Platelet-Derived Growth Factor Receptors (Platelet-Derived Growth Factor Receptor)IBA 01/2020 - 10/2008
3	IronIBA 01/2020 - 07/2018
3	Complement System Proteins (Complement)IBA 01/2019 - 05/2016
3	Glycoproteins (Glycoprotein)IBA 11/2018 - 01/2002

Therapy/Procedure

40	Therapeutics 04/2022 - 06/2005
26	Renal Dialysis (Hemodialysis) 03/2021 - 07/2007
9	Nephrectomy 01/2022 - 06/2007
9	Kidney Transplantation 01/2021 - 07/2003
5	Transplantation 01/2021 - 05/2004
3	Peritoneal Dialysis 06/2021 - 09/2014
3	Catheters 08/2020 - 07/2007
3	Ligation 01/2020 - 05/2007